ES-Firm is a guild composed of weak signals from a large number of Firmicutes genera together with Alistipes. While this ES is almost never present as a mono-dominating ES, it is present as primary or secondary ES in a majority of individuals and associates to healthy markers.
Background | Identification study | First included |
Frioux et. al (202X) | November 2022 |
Known associations | Dataset | Associations |
BMIS | acid reflux - PPI dosage (negative) (Frioux et. al (202X)) stomach acid - cmd drug intake (negative) (Frioux et. al (202X)) macrolide (negative) (Frioux et. al (202X)) ace inhibitor dosage (negative) (Frioux et. al (202X)) antihypertensive drug intake (negative) (Frioux et. al (202X)) beta blocker dosage (negative) (Frioux et. al (202X)) gout medication intake (negative) (Frioux et. al (202X)) HbA1cblood sugar level (negative) (Frioux et. al (202X)) triglyceride concentration (negative) (Frioux et. al (202X)) hsCRP inflammation marker (negative) (Frioux et. al (202X)) aHEI diet score (positive) (Frioux et. al (202X)) DASH diet score positive () (Frioux et. al (202X)) DDS diet score (positive) (Frioux et. al (202X)) age (positive) (Frioux et. al (202X)) BMI (negative) (Frioux et. al (202X)) fat mass (negative) (Frioux et. al (202X)) | |
GMR adults | age (negative) (Frioux et. al (202X)) | |
GMR infants | birth weight (positive) (Frioux et. al (202X)) age (positive) (Frioux et. al (202X)) |
Technical validation | - | - |
- | - |
Composition | Rank | Taxa |
Kingdom |
Bacteria (82.43%) Archaea (0.69%) |
|
Phylum |
Firmicutes_A (64.57%) Bacteroidota (10.55%) Verrucomicrobiota (2.56%) Firmicutes_C (2.11%) Actinobacteriota (1.37%) Proteobacteria (0.74%) Methanobacteriota (0.69%) Firmicutes (0.53%) |
|
Class |
Clostridia (63.16%) Bacteroidia (10.55%) Verrucomicrobiae (2.56%) Clostridia_A (1.41%) Negativicutes (2.11%) Coriobacteriia (1.37%) Alphaproteobacteria (0.74%) Methanobacteria (0.69%) Bacilli (0.53%) |
|
Order |
Lachnospirales (32.43%) Oscillospirales (30.73%) Bacteroidales (10.55%) Verrucomicrobiales (2.56%) Christensenellales (1.41%) Veillonellales (1.39%) Coriobacteriales (1.37%) RF32 (0.74%) Acidaminococcales (0.72%) Methanobacteriales (0.69%) Erysipelotrichales (0.53%) |
|
Family |
Lachnospiraceae (32.43%) Ruminococcaceae (18.94%) Rikenellaceae (7.92%) Acutalibacteraceae (8.28%) Akkermansiaceae (2.56%) Oscillospiraceae (3.51%) Bacteroidaceae (1.83%) CAG-74 (1.41%) Dialisteraceae (1.39%) Coriobacteriaceae (1.37%) Barnesiellaceae (0.8%) CAG-239 (0.74%) Acidaminococcaceae (0.72%) Methanobacteriaceae (0.69%) Erysipelotrichaceae (0.53%) |
|
Genus |
Agathobacter (8.99%) Faecalibacterium (8.36%) Alistipes (7.92%) Ruminococcus (5.31%) Ruminococcus_E (5.07%) Blautia (4.52%) Lachnospira (3.31%) Ruminiclostridium_E (2.76%) Akkermansia (2.56%) Gemmiger (2.51%) Coprococcus (2.45%) Fusicatenibacter (2%) Anaerostipes (1.99%) CAG-83 (1.94%) Roseburia (1.88%) Phocaeicola (1.83%) Acetatifactor (1.47%) UBA11524 (1.41%) Dialister (1.39%) Collinsella (1.37%) Dorea (1.33%) Mediterraneibacter (1.22%) CAG-180 (1.19%) ER4 (1.06%) Eubacterium_R (0.89%) Anaerobutyricum (0.82%) Barnesiella (0.8%) CAG-127 (0.76%) CAG-495 (0.74%) Phascolarctobacterium (0.72%) Methanobrevibacter_A (0.69%) CAG-217 (0.62%) CAG-45 (0.61%) Butyrivibrio_A (0.57%) Holdemanella (0.53%) Ruminococcus_H (0.51%) Eubacterium_F (0.51%) CAG-103 (0.51%) |